Journal of Biological Sciences and Medicine 2019-07-04T08:07:52+00:00 Dr. Anurag Dabas Open Journal Systems <p>The “<strong><em>Journal of Biological Sciences and Medicine</em></strong>” (JBSM) is an international open access journal in English published quarterly. The aim of JBSM is to publish rapid and peer reviewed original research articles, scientific reports, review and mini-reviews in the developing and interdisciplinary field of biological, environmental and medical sciences. We welcome original research papers covering all aspects of modern biology for publication in our journal. Aspiring young scientists, medical professionals and researchers especially in the field of biology, biomedicine, environmental sciences, agricultural sciences, forestry, biotechnology etc., are wholeheartedly encouraged to submit their valuable contributions.</p> <p>Journal of Biological Sciences and Medicine welcomes original, unpublished research papers which includes critical analysis of any aspect of all subjects from the faculty members, graduate students, independent researchers, and writers from all over the world. The scope of the journal is wide open to the International arena.</p> Alpha tocopherol: Exploring the link with Oxidative stress, Smokeless tobacco and Periodontal Disease 2019-06-30T18:28:33+00:00 Roma Kewlani Nagaraj B Kalburgi Arati C Koregol <p><strong>Background: </strong>Alpha tocopherol (vitamin E) is a radical-scavenging antioxidant that protect the cells from reactive oxygen species (ROS). Increased ROS production causes oxidative stress. The effects of smokeless tobacco on periodontal disease have fewer consideration. Taking this into concern the present study was designed to determine both saliva and serum alpha-tocopherol levels in periodontal health and disease. <strong>Materials and Methods: </strong>120 individuals of age 17 to 65 years were categorized into four groups as Group I: 30 healthy (H), group II: 30 chronic periodontitis (CP), group III: 30 smoker patients with CP, group IV: 30 smokeless tobacco chewers with CP. Vitamin E levels were determined by UV-spectrophotometer (536 nm). Statistical analysis was performed by using Analysis of variance (ANOVA) and Tukeys multiple post hoc comparison test. <strong>Results: </strong>Mean vitamin E levels in saliva and serum were found highest for Group I &amp; least in Group III. When intergroup comparison was done, the differences in the mean vitamin E concentrations in saliva were statistically significant in all except in between Group II and IV. Whereas mean serum levels were statistically significant in all except in between Group III and IV. <strong>Conclusion:</strong> Low salivary and serum level of α-tocopherol is indicative of oxidative stress associated with smoking and smokeless tobacco. &nbsp;</p> <p>&nbsp;</p> <p><strong>Keywords:</strong> Alpha tocopherol, oxidative stress, smokeless tobacco, smoking, chronic periodontitis.</p> 2019-06-30T00:00:00+00:00 ##submission.copyrightStatement## Effect of systemically administered Ornidazole and Metronidazole with or without scaling and root planing: A clinical study 2019-07-04T08:07:52+00:00 Manisha Pathak Anand Kishore Awadhesh Kumar Singh <p style="text-align: justify;">The present study evaluates and compares the clinical effects of systemic metronidazole and ornidazole in sites with or without scaling and root planing (SRP) in generalized chronic periodontitis patients in terms of gingival scores(GS), Probing depth(PD) and Bleeding on probing(BOP). A total of 40 patients suffering from chronic periodontitis (18-42 years) were selected &amp; randomly divided equally into three groups on the basis of the treatment plan. The clinical parameters were assessed at baseline i.e. day 0, day 7 and day 14 post-treatment. Clinical parameters gingival inflammation, pocket depth and bleeding on probing over a period of 14 days Ornidazole + SRP proved to be a better mode of treatment. Significant improvement was noted in all the five treatment modalities in treating chronic generalized periodontitis.</p> 2019-07-01T07:11:09+00:00 ##submission.copyrightStatement##