Anticarcinogenic effects of Soybean (Glycine max) in Mouse model System

  • Udita Singh Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Pallavi Indurkar Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Arti Saxena Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Jitendra Kumar Tripathi Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Pranav Mishra Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Narita Singh Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India
  • Arvind K Tripathi Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Abstract

Cancer is one of the rapidly growing diseases, which is now second leading cause of death. Our preexisted therapeutics has very little effect with higher range of side effects. Chemoprevention is a novel strategy which is currently based on the herbal drugs which have chemo-protective potentials. Our research work is based on the phytochemicals present in the plant which could reverse or suppress tumor growth. In present investigation we selected Glycine max (Soybean) to evaluate its anti-cancerous effects. We evaluated hepatic antioxidant profile and revealed that use of different doses of Glycine max work over GSH, Catalase activity meanwhile effect on lipid peroxidation reveal that lipid peroxidation was significantly decreased with higher doses of Glycine max. Our findings clearly suggest that Glycine max can significantly suppress or reverse tumor formation by increasing the activity of antioxidant enzymes and lipid peroxidation could be reversely altered. 

Author Biographies

Udita Singh, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Pallavi Indurkar, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Arti Saxena, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Jitendra Kumar Tripathi, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Pranav Mishra, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Narita Singh, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Arvind K Tripathi, Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

Faculty of Biotechnology & Post Doctoral Researcher

Centre for Biotechnology Studies, A.P.S. University Rewa M.P., India

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Published
2017-06-30
How to Cite
[1]
Singh, U., Indurkar, P., Saxena, A., Tripathi, J., Mishra, P., Singh, N. and Tripathi, A. 2017. Anticarcinogenic effects of Soybean (Glycine max) in Mouse model System. Journal of Biological Sciences and Medicine. 3, 2 (Jun. 2017), 9-13.
Section
Research Articles