Synthesis and characterization of silver nanoparticles using transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA) technique

  • Garima Srivastava Himalayan University, Itanagar, Arunachal Pradesh, India
  • Raghvendra Pratap Narayan Netaji Subhash Chandra Bose Government Girls Postgraduate College, Lucknow, Uttar Pradesh, India -226024
  • Pavan Kumar GenTox Research and Development, Gomti Nagar, Lucknow- 226010, India


The use of nanomaterials is rapidly increasing, while little is known about their possible ecotoxicological effects. In addition to toxicity assessment the particles were characterized by transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA). An Ag particle was within the small nanometer size range when dispersed in pure water. In media with higher ionic strength and DOC, particles tended to agglomerate. Cytotoxicity assessments showed that Ag nanoparticles caused a significant reduction in membrane integrity and cellular metabolic activity in a concentration dependent manner. The current study shows that size of particle, ionic strength and adverse effect on at low mg/l concentrations.


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How to Cite
Srivastava, G., Narayan, R. and Kumar, P. 2017. Synthesis and characterization of silver nanoparticles using transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA) technique. Journal of Biological Sciences and Medicine. 3, 1 (Mar. 2017), 1-4.
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