Anticarcinogenic effects of Soybean (Glycine max) in Mouse model System

Udita Singh, Pallavi Indurkar, Arti Saxena, Jitendra Kumar Tripathi, Pranav Mishra, Narita Singh, Arvind K Tripathi

Abstract


Cancer is one of the rapidly growing diseases, which is now second leading cause of death. Our preexisted therapeutics has very little effect with higher range of side effects. Chemoprevention is a novel strategy which is currently based on the herbal drugs which have chemo-protective potentials. Our research work is based on the phytochemicals present in the plant which could reverse or suppress tumor growth. In present investigation we selected Glycine max (Soybean) to evaluate its anti-cancerous effects. We evaluated hepatic antioxidant profile and revealed that use of different doses of Glycine max work over GSH, Catalase activity meanwhile effect on lipid peroxidation reveal that lipid peroxidation was significantly decreased with higher doses of Glycine max. Our findings clearly suggest that Glycine max can significantly suppress or reverse tumor formation by increasing the activity of antioxidant enzymes and lipid peroxidation could be reversely altered. 

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