Journal of Biological Sciences and Medicine <p>The “<strong><em>Journal of Biological Sciences and Medicine</em></strong>” (JBSM) is an international open access journal in English published quarterly. The aim of JBSM is to publish rapid and peer reviewed original research articles, scientific reports, review and mini-reviews in the developing and interdisciplinary field of biological, environmental and medical sciences. We welcome original research papers covering all aspects of modern biology for publication in our journal. Aspiring young scientists, medical professionals and researchers especially in the field of biology, biomedicine, environmental sciences, agricultural sciences, forestry, biotechnology etc., are wholeheartedly encouraged to submit their valuable contributions.</p> <p>Journal of Biological Sciences and Medicine welcomes original, unpublished research papers which includes critical analysis of any aspect of all subjects from the faculty members, graduate students, independent researchers, and writers from all over the world. The scope of the journal is wide open to the International arena.</p> Journal of Biological Sciences and Medicine en-US Journal of Biological Sciences and Medicine 2455-5266 <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a&nbsp;<a href="">Creative Commons Attribution License</a>&nbsp;that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See&nbsp;<a href="" target="_new">The Effect of Open Access</a>).</li> </ol> Effects of Manganese Exposure on Testicular Histomorphology, Serum Hormones Level and Biochemical Marker Parameters in Wistar Rats <p>Manganese is an essential trace element that can elicit a variety of toxic responses upon prolonged exposure. The aim of the present study was to elucidate the toxic effects of manganese chloride (MnCl<sub>2</sub>) exposure on testicular histomorphology, reproductive hormone levels and oxidative stress parameters in Wistar rats. Adult, colony bred male rats were divided into four groups each having eight animals. Group I served as control and received normal saline (0.5 ml/rat) as vehicle while Group II, III and IV received 50, 100 and 150 mg/kg b.wt. MnCl<sub>2</sub>/day­ orally, respectively for 60 days. The present study revealed thatthe body andrelative weight of testes, serum follicle stimulating hormone, luteinizing hormone and testosterone levels were significantly declined in MnCl<sub>2</sub> exposed rats when compared with control rats. The level of testicular thiobarbituric acid reactive substance (TBARs) was increased with concomitant decline in superoxide dismutase activity, glutathione and ascorbic acid levels. Histomorphological study of the testis in MnCl<sub>2 </sub>exposed rats revealed dose dependent degenerative and atrophic changes, exfoliation of germ cells, shrinkage of seminiferous tubules and Leydig cell nucleus. Thus, the findings of the present study suggested that exposure of MnCl<sub>2 </sub>at high doses had significant adverse impact on male reproductive endpoints.</p> Milan Chandel G C Jain ##submission.copyrightStatement## 2017-09-30 2017-09-30 3 3 1 14 Scale of murrel: A non-invasive approach to monitor heavy metals in freshwater <p>Indian freshwater murrel <em>Channa punctata </em>were maintained in a floating cage in river Yamuna at Canal Colony, Kalindi Kunj, Delhi during the summer, monsoon and winter seasons in a year. Incidence of heavy metals (Pb, Hg, Fe, Cu, As) on fish scales were investigated by employing Scanning Electron Microscopy (SEM) and Energy Disruptive X-Ray (EDX) analyser. Fish scales revealed altered elemental composition and uprooted lepidonts. The present study indicated that structural integrity of the scale is compromised under stress of heavy metals and pollutants. </p> Satyam Dwivedi Neeta Sehgal ##submission.copyrightStatement## 2017-09-30 2017-09-30 3 3 15 23 A study of Titanium nanoparticles using different technique which to be used in biological system Nanotechnology is a promising field of science and technology, to deal with the effects of engineered or manufactured nanomaterials and their applications on living organisms. In addition to toxicity valuation, the particles were characterized by different technique like transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA). Titanium nanoparticle was within the small nanometer size range when dispersed in pure water. The particles were tended to agglomerate in media with higher ionic strength. The assessments of cytotoxicity showed that Ti nanoparticles caused a significant lessening in membrane integrity and cellular metabolic activity in a concentration dependent manner. The current study shows that size of Titanium nanoparticles and their ionic strength is adequate and also can be used at low concentrations to determine adverse effect in further experimentations. Monex Kumar Gupta Anand Kumar Vishwakrama Garima Srivastava Pavan Kumar ##submission.copyrightStatement## 2017-09-30 2017-09-30 3 3 29 35 Unlocking the secrets of Good Health, Wellness and Fitness <p>In general, health is an optimal well-being that contributes significantly to quality of life free from disease and illness. Optimal health includes high-level mental, social, emotional, spiritual, and physical wellness within the parameters of heredity and personal abilities. Good health helps in sustaining an average life cycle of human being. Several factors such as nutrition and exercise are main components of a healthy life that make people mentally and physically fit. These four parts health, exercise, fitness, nutrition are a pillar for human healthy life. The HELP Philosophy says that H=Health, E=Everyone, L=Lifetime, P=Personal. Wellness is the integration of many different components such as mental, social, emotional, spiritual, and physical factors that expand one’s potential to live a quality of life, work effectively and make significant contribution to society. It is the reflection of how one feels about life as well as one’s ability to function effectively. In the present review, an attempt has been made to shed some light on the much ignored but equally relevant matters of health and explore the possibilities of mass awakening in the process of attaining good health in with a teamwork of diet, exercise, fitness and a supportive community.</p> Kriti Verma Rashmi Srivastava ##submission.copyrightStatement## 2017-09-30 2017-09-30 3 3 24 28