Journal of Biological Sciences and Medicine <p>The “<strong><em>Journal of Biological Sciences and Medicine</em></strong>” (JBSM) is an international open access journal in English published quarterly. The aim of JBSM is to publish rapid and peer reviewed original research articles, scientific reports, review and mini-reviews in the developing and interdisciplinary field of biological, environmental and medical sciences. We welcome original research papers covering all aspects of modern biology for publication in our journal. Aspiring young scientists, medical professionals and researchers especially in the field of biology, biomedicine, environmental sciences, agricultural sciences, forestry, biotechnology etc., are wholeheartedly encouraged to submit their valuable contributions.</p> <p>Journal of Biological Sciences and Medicine welcomes original, unpublished research papers which includes critical analysis of any aspect of all subjects from the faculty members, graduate students, independent researchers, and writers from all over the world. The scope of the journal is wide open to the International arena.</p> Journal of Biological Sciences and Medicine en-US Journal of Biological Sciences and Medicine 2455-5266 <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a&nbsp;<a href="">Creative Commons Attribution License</a>&nbsp;that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See&nbsp;<a href="" target="_new">The Effect of Open Access</a>).</li> </ol> Alternations of selenium and malondialdehyde status in chronic kidney disease <p>Chronic kidney disease (CKD) is a major public health burden worldwide. CKD patients have cardiovascular risk factors such as diabetic mellitus and hypertension. These factors are associated with oxidative stress which accelerates renal injury in CKD patients. This study aimed to determine selenium (antioxidant trace element) and malondialdehyde (MDA, oxidative stress marker) in patients with CKD. Serum selenium and MDA levels are analyzed in CKD patients (n=20) compared with values observed in control (n=20). Serum urea, creatinine and MDA levels were determined with spectrophometric methods and serum selenium level was measured by atomic absorption spectrophotometry. Serum selenium and MDA in CKD patients showed significant differences in comparison with control – MDA 2.42 ± 0.57 vs. 0.98 ± 0.09 µmol/L (p&lt;0.001) and selenium 81.52 ± 10.24 vs. 105.46 ± 10.53 µg/L (p&lt;0.001). A significant negative correlation was observed between serum selenium and MDA in CKD patients (r = - 0.88, p &lt; 0.0001), while there was a significant positive correlation of selenium level with creatinine clearance in CKD (r = 0.714, p &lt;0.001). There is imbalance between oxidative stress and antioxidant status in CKD. We suggest MDA could be used as oxidative marker for progressive kidney diseases.</p> Myat Mon Khine Htay Htay Nyo Nyo ##submission.copyrightStatement## 2018-10-03 2018-10-03 4 3 1 4 Potential of Helianthus annuus for phytoremediation of multiple pollutants in the environment: A Review <p>The development of various industrial contaminants especially heavy metals poses a severe environmental threat. Heavy metals are continuously polluting the ecosystem and these are harmful to the human being and other biota of the ecosystem. Phytoremediation is a cost-effective method for remediation of the polluted soil and water. The review represents the status of this technique with special emphasis on phytaccumulation of the multi-pollutants like heavy metals, hydrocarbons and other pollutants using <em>Helianthus annuus</em>, a hyperaccumulator plant. Various mechanisms are known for absorption and transportation of heavy metals inside the plant body through metal binding proteins viz. metallotheiones, phytochelatins and antioxidant enzymes which enhance the accumulation of metal. Microbial association with plants also plays a significant role in the enhancement of remediation of these pollutants and employ of genetic engineering also enhances the phytoaccumulation of heavy metals.</p> Priti Chauhan Jyoti Mathur ##submission.copyrightStatement## 2018-10-03 2018-10-03 4 3 5 16 Significance of medicinal plants against typhoid fever: Possible mechanism, effectiveness and outcomes <p>Typhoid fever one of the most severe bacterial disease have affected millions over the decades. It usually being treated with the administration of antibiotics as well as homeopathic medicines and traditional medicines which includes several medicinal plants. Such use of antibiotics against <em>Salmonella typhi</em> has increased the danger of increasing resistance of it against used antibiotics and thus decreasing the chances of its treatment in future. Homeopathic medicines prepared from several medicinal plants have been reported to be very effective against the <em>S. typhi</em> and its variants, thus have increased the chances of its treatment. Pharmacological profile of such medicinal plants extracts is still widely unknown and need further research. Moreover, all so far used medicinal plants, required pharmacological screening for their effectiveness against the effects of <em>S. typhi</em>.</p> Anand Singh Pavan Kumar Rashmi Srivastava ##submission.copyrightStatement## 2018-09-30 2018-09-30 4 3