Journal of Biological Sciences and Medicine <p>The “<strong><em>Journal of Biological Sciences and Medicine</em></strong>” (JBSM) is an international open access journal in English published quarterly. The aim of JBSM is to publish rapid and peer reviewed original research articles, scientific reports, review and mini-reviews in the developing and interdisciplinary field of biological, environmental and medical sciences. We welcome original research papers covering all aspects of modern biology for publication in our journal. Aspiring young scientists, medical professionals and researchers especially in the field of biology, biomedicine, environmental sciences, agricultural sciences, forestry, biotechnology etc., are wholeheartedly encouraged to submit their valuable contributions.</p> <p>Journal of Biological Sciences and Medicine welcomes original, unpublished research papers which includes critical analysis of any aspect of all subjects from the faculty members, graduate students, independent researchers, and writers from all over the world. The scope of the journal is wide open to the International arena.</p> Journal of Biological Sciences and Medicine en-US Journal of Biological Sciences and Medicine 2455-5266 <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a&nbsp;<a href="">Creative Commons Attribution License</a>&nbsp;that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See&nbsp;<a href="" target="_new">The Effect of Open Access</a>).</li> </ol> Significant correlation between high motility and P450- aromatase expression in human spermatozoa - an immunochemistry based study <p>Study was planned to evaluate the correlation between sperm motility, an important functional parameter of spermatozoa and aromatase P450 expression in human spermatozoa. Total 70 random seminal samples were included in the present study. Seminal samples from men undergoing seminal investigations for couple infertility were collected. Immunochemical localization with specific monoclonal antibodies against the P450- aromatase enzyme with washed seminal slides was carried out and the results correlated with spermatozoon motility evaluation retrospectively. Expression of aromatase P450 was assessed by assigning 1+ to least and 4+ to highest. The 94.6% cases of spermatozoa showing immunochemical positive grading &gt;3+ for -aromatase P450, had motility greater than 70%. Similarly 94% cases show &lt;2+ intensity of aromatase P450 expression on spermatozoa found with motility of less than 70%. The study suggests that the spermatozoa aromatase P450 produced estradiol might be play an important role in spermatozoa motility.</p> Pankaj K Sharma Kapil Kumar S Jayaraman ##submission.copyrightStatement## 2017-12-31 2017-12-31 3 4 1 6 Association of respiratory health of women and housing pattern: a comparative study of two tribes of Maharashtra <p style="text-align: justify;">Almost 1.6 million people die every year due to indoor air pollution that means 1 death occurs per second. In India, this is a least focused and discussed area in rural settings and perhaps never studied in tribal population. Overall, 8% of Indian population comprises of tribes. The present study was carried out to show that association of respiratory health and indoor air pollution among tribal women belongs to two different tribal groups residing in interior locations of Maharashtra, India. A longitudinal study was conducted among Bhill (n = 46) and Mahadev Koli (n = 60) women, during rain and summer. Non probability purposive sampling was used to select the sample. Interview schedules for respiratory health and housing pattern were collected from women on respiratory health. Independent sample t- test shows significant difference in Forced Vital Capacity (FVC) post figures (P value = 0.02) during both the seasons. More obstruction is observed among Mahadev Koli women (60.78%). We conclude that, rudimentary traditional housing pattern in combination of modern infrastructure invasion plays important role in respiratory health of selected tribes. Prolonged wheezing and associated headache indicates presence of smaller air way obstruction and Chronic Obstructive Pulmonary Diseases (COPD). Construction type, material used to build a house and seasonal differences in both the locations are significant factor for obstruction.</p> Charulata Nandre Shaunak Kulkarni ##submission.copyrightStatement## 2017-12-30 2017-12-30 3 4 7 16 Assessment of mucus transport rate in the human lung airways using mathematical model <p style="text-align: justify;">In this study, a planar two layer mathematical model is presented to study the mucus transport in the human lung airways under steady state condition due to cilia beating and certain immotile cilia forming porous matrix bed in serous sub-layer in contact with the epithelium and air-motion by considering mucus as a visco-elastic fluid. The effect of air-motion due to external forces and other processes is considered by prescribing shear stress at mucus air interface. It is seen that the mucus transport rate increases as the pressure drop, shear stress due to air-motion, the velocity generated by cilia tips and porosity parameter increase. It is noted that the effect of gravity is similar to that of the pressure drop. It is also observed that transport rate of mucus decreases as the viscosity of serous layer fluid or mucus increases, but any increase in mucus viscosity at its higher values does not seem to affect the mucus transport rate. It is also seen that for given total depth of serous sub-layer and mucus layer, there exists a serous fluid layer thickness for which mucus transport is maximum. It is also seen that mucus transport rate increases as its shear modulus of elasticity decreases i.e. mucus transport increases as the relaxation time increases.</p> Shivesh Mani Tripathee ##submission.copyrightStatement## 2017-12-31 2017-12-31 3 4 17 25 Impact of smokeless tobacco use on pregnant Indian women <p style="text-align: justify;">Smokeless tobacco is a product consisting of tobacco or a tobacco blend that is used other than smoking. In Maharashtra the pattern of tobacco use is slightly different where smokeless tobacco is preferred over smoking. In the present study is focused to understand the impact of smokeless tobacco use on pregnant Indian women and assess adverse effects on feto-maternal outcome. The study is a hospital based case control study with sample size 591. Women who reside in <em>Chawl</em> type of resident, lower education level, homemaker/housewife, lesser family income and Marathi mother tongue are significantly associated with tobacco use and have prevalence of anaemia 77.32% among the pregnant women. The women who are tobacco users have 2 times higher risk of having anaemia as compared to tobacco non user women, (OR: 2.193, CI: 1.240 – 3.877), (p = 0.007). Women who delivered in the government hospital have 3 times higher chance of having anaemia as compared to the private hospital (OR: 3.268, CI: 1.889 – 5.652), (p = 0.000**). The illiterate have 9 times higher risk of having anaemia (OR: 9.545, CI: 2.191 – 41.592), (p = 0.003*) compared to post graduate.</p> Hemlata Shedge Shaunak Kulkarni ##submission.copyrightStatement## 2017-12-31 2017-12-31 3 4 26 34 Haematological studies on Trichogaster fasciatus fish infected with Clinostomum complanatum metacercariae <p style="text-align: justify;">Parasitic infections in general and helminth infections in particular may potentially reduce the quality and quantity of yield in aquaculture industry. Considering the significant role of various blood components in the diagnosis of diseases, we collected blood sample from the <em>Trichogaster fasciatus </em>fish infected with excysted progenetic metacercariae of <em>Clinostomum complanatum</em>. A number of blood parameters were analysed and compared with non-infected blood sample of the fish under study. Since, the haematological parameters provide a valuable tool for monitoring the fish health, the present findings may be exploited as a pilot study to understand the fish health and disease condition. In the present study, we observed significant reduction in the level of blood parameters such as RBC, Hb concentration, HCT, MCV, MCH, PLT, MPV, PDW and RDW in the infected fish as compared to the non-infected fish. It is suggested that the level of infection can elicit a stress response in the host which can be correlated with changes in the haematological parameters and may be helpful in detecting diseases and serious illness conditions in the infected fishes.</p> Shabnam Khan Sakil Ahmed M.K. Saifullah ##submission.copyrightStatement## 2017-12-31 2017-12-31 3 4 35 39 Identification of digenetic trematode of the genus Neopodocotyle from fresh water fish Bagarius bagarius (Ham.) of Gomati River <p style="text-align: justify;">Fish serves as an important food for man due to its high protein content. However, majority of fishes carry heavy infection of helminthes parasites reducing the food value of fish and can also lead to fish mortality. Hence, detailed study of these parasites is important for understanding the nature and type of infections. In the present work, a new species of digenetic trematode <em>Neopodocotyle jaunpurensis</em> of the genus <em>Neopodocotyle </em>was described, obtained from the intestine of a fresh water fish<em> Bagharius bagarius</em> (Ham.) from Gomati River, Jaunpur. It differs from other species of <em>Neopodocotyle </em>in having ratio of sucker, position of the genital pore, ovary and extension of vitellaria.</p> Siddhartha Shankar Singh GC Singh ##submission.copyrightStatement## 2017-12-31 2017-12-31 3 4 40 43