Study of Titanium nanoparticles in biological system using different techniques

  • Monex Kumar Gupta GenTox Research and Development Gomti nagar, Lucknow, 226010
  • Anand Kumar Vishwakrama GenTox Research and Development Gomti nagar, Lucknow, 226010
  • Garima Srivastava GenTox Research and Development Gomti nagar, Lucknow, 226010
  • Sujeet Pratap Singh Amity University, Gomti Nagar Extension, Lucknow, Uttar Pradesh 226010, India
  • Pavan Kumar Research Scientist GenTox Research and Development Gomti nagar, Lucknow, 226010
Keywords: Titanium nanoparticle, Transmission Electron Microscope (TEM), Nanomaterial, Toxicity

Abstract

Nanotechnology is a promising field of science and technology that deals with the effects of engineered or manufactured nanomaterial and their applications on living organisms. In addition to toxicity evaluation, these particles were characterized by different techniques like transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA). Titanium nanoparticle was within the small nanometer size range when dispersed in pure water. The particles were tended to agglomerate in media with higher ionic strength. The assessments of cytotoxicity showed that Ti nanoparticles caused a significant lessening in membrane integrity and cellular metabolic activity in a concentration dependent manner. The current study shows that size of Titanium nanoparticles and their ionic strength is adequate and also can be used at low concentrations to determine adverse effect in further studies.

Author Biographies

Monex Kumar Gupta, GenTox Research and Development Gomti nagar, Lucknow, 226010
GenTox Research and Development
Gomti nagar, Lucknow, 226010
Anand Kumar Vishwakrama, GenTox Research and Development Gomti nagar, Lucknow, 226010
GenTox Research and Development
Gomti nagar, Lucknow, 226010
Garima Srivastava, GenTox Research and Development Gomti nagar, Lucknow, 226010
GenTox Research and Development
Gomti nagar, Lucknow, 226010
Sujeet Pratap Singh, Amity University, Gomti Nagar Extension, Lucknow, Uttar Pradesh 226010, India

Amity University, Gomti Nagar Extension, Lucknow, Uttar Pradesh 226010, India

Pavan Kumar, Research Scientist GenTox Research and Development Gomti nagar, Lucknow, 226010
Research Scientist
GenTox Research and Development
Gomti nagar, Lucknow, 226010

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Published
2017-09-30
How to Cite
Gupta, M., Vishwakrama, A., Srivastava, G., Singh, S. P., & Kumar, P. (2017, September 30). Study of Titanium nanoparticles in biological system using different techniques. Journal of Biological Sciences and Medicine, 3(3), 27-32. Retrieved from http://jbscim.com/index.php/jbsm/article/view/63
Section
Research Articles